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Interpretation of Population typical values


#1

Dear all,

Please let me know how to interpret the typical value obtain from the PK models with respect to different covariates.

Below are some of the examples,

|Parameter|Typical Value|

|RACEO on Vc|-0.102|
|ALT on Vc|-0.114|
|cov(IIV on Vc, IIV on CL)|0.007|

Thanks for your inputs.
MSMN