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Interpretation of Population typical values


Dear all,

Please let me know how to interpret the typical value obtain from the PK models with respect to different covariates.

Below are some of the examples,

|Parameter|Typical Value|

|RACEO on Vc|-0.102|
|ALT on Vc|-0.114|
|cov(IIV on Vc, IIV on CL)|0.007|

Thanks for your inputs.