@vijay Calculation speed: PKNCA takes minimal time (<=1 second) for most calculations in clinical studies (10s to 100s of subjects). For simulated data sets, it could take longer, but typically the NCA calculations would be faster than the simulations. Also, since PKNCA is R-based, it can likely be run on the same system doing the simulations.
@Tim_Nicholas Reporting: PKNCA does not have a reporting function beyond the
summary function. There will likely be a future package that assists with reporting.
@Dinko_Rekic PKNCA currently calculates the AUC % extrapolated based on the Clast,observed only. In a future version, the user will have more control over the calculations and can choose. Can you please add this feature request to the GitHub issues page?
@ksl Currently, PKNCA does not allow for terminal point selection in half-life calculations. Can you please add this feature request to the GitHub issues page?