I’m pretty new here but I’m trying to figure out a way to carry out Bayesian estimation of Vd and Cl following the acquisition of a serum drug concentration to get more accurate estimates of these PK parameters.
I’ve built a PopPK model in NONMEM and have implemented it in Shiny here: www.bit.ly/VancoDoseR
I want to be able to update the predictions after acquiring 1 actual drug level.
Any leads would be most appreciated.
Thank you very much.