It would be interesting to take a snapshot survey of R packages and open source Pharmacometrics / Clin Pharm tools to see what was available, where there is overlap, where there are gaps with the aim to come up with a plan for filling gaps in functionality, harmonising, directing effort in future. So if funding was made available, what would a given developer focus on first to add most value?
Bill Denney has done some excellent work collating packages that are available on CRAN in the Pharmacokinetics Task View: https://cran.r-project.org/view=Pharmacokinetics
With tools such as nlmixr, stan, saemix, mlxR, mrgsolve, PKPDsim, RxODE, PopED, PFIM, xpose, PsN etc. there are MANY tools out there to help us get our jobs done. But are there neat ways to tie these together into workflows? Is there a (standardised) library of basic PK models across these tools? What’s missing from our toolkit?