Hi there,
I am new here, and I am not sure if it is acceptable to share a hand-made code.
However, I think this is not a commercial advertisement. So, I am sharing my code, here.
Since I felt that it was a time-consuming thing to predict the tissue-to-plasma partition coefficient (Kp) through the method of Rodgers and Rowland on Excel or a manual calculator, I made a code to calculate it on a web browser as a part of my hobby.
You can see the code at GitHub - misol/kp_predictor: The tissue-to-plasma partition coefficient predictor. The prediction methods were presented by Rodgers and coworkers in 2005, 2006, and 2007. . The equation in the literature will estimate Kpu, but the code will return Kp (instead of Kpu) after multiplying Kpu and fup ( https://github.com/misol/kp_predictor/blob/e75b874dfbb569042bbe5fdfbe05dd5edf87152a/kp_predictor/js/js.js#L1609C3-L1609C43 ).
Especially, Rodgers and Rowland’s method is expressed at https://github.com/misol/kp_predictor/blob/e75b874dfbb569042bbe5fdfbe05dd5edf87152a/kp_predictor/js/js.js#L1453-L1614 as a form of Javascript code.
Since this code is not reviewed by other researchers, there might be some mistakes which I could not find yet. Please let me know if there is any concern.
Thank you.
Min-Soo